Biochemistry and Physiology of Anaerobic Bacteria

Hardcover  XVII, 270 pp, 71 illus  ISBN 0387955925      £107.00

During the past twenty years, multitudes of exciting discoveries in the field of anaerobic bacteria have been made. Biochemistry and Physiology of Anaerobic Bacteria explores the full range of these microorganisms. Many anaerobes have been found to have the uniquely fascinating quality of being able to survive, indeed even thrive, in extreme environments. Anaerobic bacteria often do not require oxygen, can survive extremes in temperature, and can withstand the presence of toxins and heavy metals. In addition, these organisms have very different metabolic processes than "conventional" microorganisms. The wide diversity of metabolism in anaerobes is only part of the story. They have distinct energies, cytochromes, electron transport proteins, hydrogenases and dehydrogenases. Their molecular biology, physiology, and ability to use many types of electron receptors (CO2, sulfur, nitrogen and metal oxides) are also extraordinary. With practical applications ranging from wastewater treatment to food storage issues, clinical diagnosis and treatment of a wide range of medical conditions to decontamination of heavy metal exposures Biochemistry and Physiology of Anaerobic Bacteria will prove indispensable to researchers and students alike.

Contents: Anaerobes in the Recyling of Elements in the Biosphere * The Diversity of Energy Sources of Microorganisms * Mechanism of Hydrogen Activation * Reductive Activation of Aerobically Purified Desulfovibrio vulgaris Hydrogenase: Characterization of the Catalytic H Cluster * Iron-Sulfur Cluster Biosynthesis * Genes and Proteins Involved in Nickel Dependent Hydrogenase Expression * Genes and Genetic Manipulations of Dusulfovibrio * Function and Assembly of Electron Transport Complexes in Desulfovibrio vulgaris * Iron-Sulfur Proteins in Anaerobic Eukaryotes * Oxygen and Anaerobes * One-Carbon Metabolism in Methanogenic Anaerobes * Selenium-Dependent Enzymes from Clostridia * How the Diverse Physiological Potentials of Acetogens Determine their in situ Realities * Electron Transport System in Acetogens * Microbial Inorganic Sulfur Oxidation: The APS Pathway * Reduction of Metals and Non-essential Elements by Anaerobes * Chemolithoautotrophic Thermophilic Iron (III)-Reducer * Electron Flow in Ferrous Biocorrosion