The Immunoglobulin Facts Book

Paperback  296 pages  ISBN 012441351X

This book discusses immunoglobulins, more commonly known as antibodies, that represent an essential component of the body's immune response. The purpose of this book, as with the other volumes in the Facts Book series that has established itself as the best source of easily-accessible and accurate facts about protein group, is to provide the answers to questions such as:

• How do you keep track of basic information on the proteins you work with?
• Where do you find details of their physicochemical properties, amino acid sequences, and structure?
• Are you tired of scanning review articles, primary papers and databases to locate that elusive fact?

This volume is the first published reference for all functional and ORF immunoglobulin genes. Introductory chapters present up-to-date information on immunoglobulin structural and biological properties, chain synthesis, gene chromosomal localization, and organization of the IGH, IGK and IGL loci. This is followed by entries on all the 203 functional and ORF variable, diversity, joining and constant genes in man, and provides the first complete overview of the potential repertoire of the immunoglobulin heavy, kappa and lambda loci. It will be of value to research immunologists as well as others working in immunogenetics, genetics, cell biology and biochemistry in universities and industry.