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Agrobacterium: From Biology to Biotechnology
Edited by Tzfira, Tzvi; Citovsky, Vitaly
Springer
2008
Hardcover 750 pp ISBN 9780387722894
£88.00
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Agrobacterium is the only cellular organism on Earth that is naturally capable of transferring genetic
material between the kingdoms of life, from prokaryotes to eukaryotes. Studies have uncovered a wealth
of information on the process of Agrobacterium-mediated genetic transformation and on the bacterial and host
cell factors involved in the infection. Agrobacterium has been shown to genetically transform, under laboratory
conditions a large number of plant species and numerous non-plant organisms, indicating the truly basic nature
of the transformation process. It is therefore not surprising that Agrobacterium and the genetic transformation
itself have also become the focus of numerous ethical and legal debates.
This is a comprehensive book on Agrobacterium research, including its history, application, basic biology
discoveries, and effects on human society. Although the book largely focuses on providing a detailed review
of virtually all molecular events of the genetic transformation process, it also provides coverage of ethical and
legal issues relevant to the use of Agrobacterium as a "genetic transformation machine". The result is an
all-inclusive text which readers, including scientists and students involved in plant genetic engineering, will find
useful as a reference source for all major aspects of the Agrobacterium-mediated genetic transformation
of plant and non-plant organisms.
Written for: Plant science researchers
Contents
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- Agrobacterium: a disease-causing bacterium.
- A brief history of research on Agrobacterium tumefaciens:
1900-1980.
- Agrobacterium and plant biotechnology.
- The Agrobacterium tumefaciens C58 genome.
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Agrobacterium-taxonomy of plant-pathogenic Rhizobium species.
- The initial steps in Agrobacterium tumefaciens
pathogenesis: chemical biology of host recognition.
- Agrobacterium-host attachment and biofilm formation.
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Production of a mobile T-DNA by Agrobacterium tumefaciens.
- Translocation of oncogenic T-DNA and
effector proteins to plant cells.
- Intracellular transport of Agrobacterium T-DNA.
- Mechanisms
of T-DNA integration.
- Agrobacterium tumefaciens-mediated transformation: patterns of T-DNA
integration into the host genome
- Function of host proteins in the Agrobacterium-mediated plant
transformation process
- The oncogenes of Agrobacterium tumefaciens and Agrobacterium rhizogenes
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Biology of crown gall tumors
- The cell-cell communication system of Agrobacterium tumefaciens.
- Horizontal gene transfer
- Agrobacterium-mediated transformation of non-plant organisms.
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The bioethics and biosafety of gene transfer.
- Agrobacterium-mediated gene transfer: a lawyer€s perspective.
To find similar publications, click on a keyword below:
Agrobacterium-mediated transformation
: biofilms
: biological conversion
: biology, general
: biotechnology
: gene transfer
: genetically modified organisms
: genomics
: plant science
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