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Phycotoxins: Chemistry and Biochemistry
Edited by Luis Botana
Blackwell
June 2007
Hardback 368 ISBN 9780813827001
£115.00
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Phycotoxins: Chemistry and Biochemistry presents the most updated information available
on phycotoxins. Major emphases are given to chemistry and biochemistry, while minor emphases are
given to the aspects of origin, toxicology, or analytical methodology. The book discusses 16 phycotoxins,
7 on those affecting the nervous systems, 4 affecting other body systems; and 4 with undefined targets.
An alphabetical listing of toxins presented includes: Azaspiracids; Brevetoxins; Cyanobacterial toxins;
Domoic acid; Gambierols; Gymnodimines, prorocentrolides, spirolides, pinnatoxins and cyclic imines in
general; Maitotoxin; Okadaic acid and dinophysistoxins; Palytoxins and ostreocins; Pectenotoxins;
Polycavernosides; and Yessotoxins. In addition, several mechanistic aspects of newer or emerging
toxins are covered such as amphidinols or gymnocine. Information presented and coverage of each
toxin follows the following distribution: background and toxicology (10%); chemistry, biochemistry
and metabolism (75%); mechanism of action (10%); and analytical methodology (5%).
The detailed information on chemistry inthis book provides investigators, regulators, food technologists
and toxicologists an updated basis on which research in other areas such as toxicology, mechanism of
action, analytical methodology and pharmacology can be successfully developed and expanded.
Contents
Gambierols
Brevetoxins: Structure, Toxicology and Origin
Chemistry of Maitotoxin
Biochemistry of Maitotoxin
The Chemistry of Palytoxins and Ostreocins
Biochemistry of Palytoxins and Ostreocins
Chemistry of Cyanobacterial Neurotoxins - Anatoxin-a: Synthetic Approaches
Anatoxin-a and Analogues: Discovery, Distribution and Toxicology
Pectenotoxins
Chemistry, Orgins and Distribution of Yessotoxin and it's Analogues
Pharmacology of Yessotoxin
Chemistry of Diarrhetic Shellfish Poisoning Toxins
The Molecular and Integrative Basis to Domoic Acid Toxicity
Hepatotoxic Cyanobacteria
Polycavernosides
Structural Assignment and Total Synthesis of Azaspiracid-1
Biochemistry of Azaspiracid Poisoning Toxins
The Cyclic Imines: An Insight into this Emerging Group of Bioactive Marine Toxins
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