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Synthesis and Characterization of Glycosides
Edited by Marco Brito-Arias
Springer
2007
Hardcover 352 pp ISBN 9780387262512
£59.00
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This book contains the best known approaches for preparing the main types of glycosides in a short and
comprehensive study. It also includes synthetic pathways of challenging glycosides known as antiviral or
antineoplasic drugs, or synthetic substrates used for enzymatic detection including those used as substrates
for detection of gene markers in plant biotechnology. Special attention is made on the structural
characterization, providing the basic tools for the structural assignment through NMR, X-Ray and mass
spectra techniques.
Some of the chapters cover strategies for preparation of antiviral and antineoplasic drugs included in a
drug design course.
Of interest to senior undergraduates, graduate students, and professionals specialized in those
fields related to pharmaceutical chemistry, natural product synthesis, drug design and sugar chemistry. Some
of the chapters cover strategies for preparation of antiviral and antineoplasic drugs included in a drug
design course. This can be also useful to professionals oriented to the pharmaceutical and plant biotechnology areas.
Contents
- Introduction: Glycosides-Synthesis and Characterization.
- O-Glycoside Formation.
- N-Glycosides.
- Nucleoside Mimetics.
- C-Glycosides.
- Glycoconjugates.
- Hydrolysis of Glycosides
- Nuclear Magnetic Resonance of Glycosides.
- X-Ray Diffraction of Glycosides.
- Mass Spectrometry of Glycosides.
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