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Phenolic Compound Biochemistry
Wilfred Vermerris and Ralph Nicholson
Springer
November 2006
Hardcover 276 pp ISBN 9781402051630
£80.00
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How does the consumption of red wine reduce heart disease? How does a plant battle an invading fungus
using physical and chemical defense mechanisms? How are tannins used in leather production synthesized?
These are just a few examples that illustrate the chemical diversity and use of phenolic compounds, the topic
of 'Phenolic Compound Biochemistry'.
This book is written for researchers, instructors, advanced undergraduate students and beginning graduate
students in the life sciences who wish to become more familiar with these and many other intriguing aspects
of phenolic compounds. Topics covered include nomenclature, chemical properties, biosynthesis, including
an up-to-date overview of the genetics controlling phenolic metabolism, isolation and characterization of phenolic
compounds, phenolics used in plant defense, and the impact of phenolics on human health.
The book is written
in an accessible style, and assumes only basic knowledge of organic chemistry, biochemistry and cell physiology.
More than 300 chemical structures and reaction schemes illustrate the text.
Contents
Preface.
1. 1. Definitions. 2. Classification. 3. Classes of phenolic compounds. 4. References.
2. 1. The benzene ring. 2. References.
3. 1. Introduction. 2. Protein isolation and purification. 3. Gene cloning strategies. 4. Isolation and characterization
of recombinant proteins. 5. Carbohydrate catabolism. 6. The shikimate pathway. 7. The general phenylpropanoid
pathway. 8. Biosynthesis of phenolic acids. 9. Biosynthesis of flavonoids and condensed tannins. 10. Monolignol
biosynthesis. 11. Lignan biosynthesis. 12. Lignin biosynthesis. 13. Hydroxycinnamic acid biosynthesis. 14.
Biosynthesis of sinapoyl esters. 15. Coumarin biosynthesis. 16. Stilbene biosynthesis. 17. Biosynthesis
of gallotannins and ellagitannins. 18. References.
4. 1. Introduction. 2. Isolation of phenolic compounds. 3. Identification and characterization of phenolic
compounds. 4. Visualization of phenolic compounds in planta using histochemical stains. 5. References.
5. 1. The principles of mass spectrometry. 2. New developments in mass spectrometry. 3. Quantitation.
4. References.
6. 1. Preformed antimicrobial and insecticidal metabolites. 2. Compounds formed in response to pathogen attack.
3. References.
7. 1. Introduction. 2. Antioxidant properties. 3. Disease prevention. 4. Activity against toxins. 5. References.
Appendix-compounds.
Index.
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