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Large scale genome sequence processing
Masahiro Kasahara & Shinichi Morishita
Imperial College Press
July 2006
Hardback 248 pp ISBN 1860946356
£39.00
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Efficient computer programs have made it possible to elucidate and analyze large-scale genomic sequences.
Fundamental tasks, such as the assembly of numerous whole-genome shotgun fragments, the alignment
of complementary DNA sequences with a long genome, and the design of gene-specific primers or oligomers,
require efficient algorithms and state-of-the-art implementation techniques. This textbook emphasizes basic
software implementation techniques for processing large-scale genome sequences and provides executable
sample programs.
Of interest to advanced undergraduate students in computer science and biology; biotechnology and computer industry
and non-experts interested in advanced genome processing algorithms.
Contents
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Simple String Search
- Sorting
- Lookup Tables
- Suffix Arrays
- Space-Efficient String Search
- Approximate String Search
- Seeded Alignments
- Whole Genome Shotgun Sequencing.
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