Parasitic Flatworms: Molecular Biology, Biochemistry, Immunology and Physiology

Edited by A G Maule and N J Marks 
CABI  June 2006  

Hardback  480 pages  ISBN 9780851990279      £100.00
This book examines recent research into the molecular biology, genomics and transcriptomics of, and novel control strategies for, flatworm parasites. These include Cestodes (tapeworms) and Trematodes (flukes, schistosomes etc), which are the cause of a number of diseases of medical and veterinary importance. The book explores three main areas: phylogeny, genetics and transcriptomes; immunobiology, host-parasite interaction and control; and protein function, metabolism and physiology. Where appropriate, comparisons are made between different parasitic flatworms and between parasitic and free-living species. The book concludes by exploring future avenues for research. Contributors to the book include leading authorities from Europe, North and South America, and Australia.

Readership: Researchers in parasitology, immunology and infectious diseases


Part I: Phylogeny, Genetics and Transcriptomes

  • The Evolution of Parasitism in Flatworms, D T J Littlewood, Natural History Museum, UK
  • Genomes and Genomics of Parasitic Flatworms, D A Johnston, Natural History Museum, UK
  • Genetic Discrimination of Echinococcus Species and Strains, D P McManus, University of Queensland, Australia
  • Ribosomal DNA Variation in Parasitic Flatworms, D Blair, James Cook University, Australia
  • Genetic Studies on Monogeneas with Emphasis on Gyrodactylus, C O Cunningham and I Matejusová, FRS Marine Laboratory, Aberdeen, UK
  • The Schistosome Transcriptome, S Verjovski-Almeida and R DeMarco, Universidade de Sao Paulo, Brazil
  • Transgenic Flatworms, C G Grevelding, Justus-Liebig-University Giessen, Germany
Part II: Immunobiology, Host-Parasite Interaction and Control
  • Immunobiology of Schistosomes, S G Forrester, University of Ontario, Canada and E J Pearce, University of Pennsylvania, USA
  • Cestode Infection: Immunological Considerations From Host and Tapeworm Perspectives, D M McKay, McMaster University, and R A Webb, York University, Canada
  • Parasitic Flatworms: Signal Transduction at the Host-Parasite Interface, T P Yoshino, J J Vermeire and J Humphries, University of Wisconsin-Madison, USA
  • Parasite Effects on the Snail Host Transcriptome, M Knight and N Raghavan, Biomedical Research Institute, USA
  • Developments in the chemotherapy of parasitic flatworms, G C Coles, University of Bristol, UK
  • Drug Resistance in Schistosomes, T A Day, Iowa State University, USA and S Botros, Theodor Bilharz Research Institute, Egypt
  • Praziquantel: Mechanism of Action, R M Greenberg, Marine Biological Laboratory, Woods Hole, MA, USA
  • Cestode Vaccine Development, M W Lightowlers, University of Melbourne, Australia
  • The Development of a Schistosome Vaccine, R A Wilson and P S Coulson, University of York, UK
Part III: Protein Function, Metabolism and Physiology
  • Flatworm Parasite Proteomics, R M Morphew, J Barrett and P M Brophy, University of Wales, UK
  • Proteases in Trematode Biology, J P Dalton, University of Technology, Australia, C R Caffrey, M Sajid, University of California, USA, C Stack, S Donnelly, University of Technology, Australia, A Loukas, T Don, Queensland Institute of Medical Research, J McKerrow, University of California, USA, D W Halton, Queen€s University Belfast, UK and P J Brindley, Tulane University Health Sciences Center, USA
  • Signalling Molecules and Nerve-Muscle Function, A G Maule, N J Marks and T A Day
  • Unusual Aspects of Metabolism in Flatworm Parasites, A G M Tielens and J J van Hellemond, Utrecht University, Netherlands
  • Glycoconjugate Structures, M Wuhrer, Leiden University Medical Center, Netherlands and R Geyer, University of Giessen, Germany
  • Gene Silencing in Flatworms using RNA interference, P J Skelly, Tufts University School of Veterinary Medicine, USA

To find similar publications, click on a keyword below:
CABI : New 2006 : animal science : biochemistry : flatworms : immunology : molecular biology : parasite : physiology : trematodes

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