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Apoptosis - The Life and Death of Cells
Christopher Potten and James Wilson
CUP
November 2004
Hardback 226 pages ISBN 0521622719
£60.00
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Paperback 226 pages ISBN 052162679X
£28.00
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The concept of programmed cell death, or apoptosis, has exploded into a major scientific field of interest
for cell biologists, oncologists, and many other biomedical researchers. Apoptosis occurs throughout
the lifetime of most multicellular organisms. During development, for example, the selective death of cells is
vital to remove tissue between the digits to produce fingers and toes. Apoptosis is also necessary to destroy
cells that represent a threat to the integrity of the organism, for example cells infected by a virus. In many
cancers the genes regulating apoptosis are defective, producing immortal, continuously proliferating cells.
This book discusses the philosophical and technical difficulties in defining the moment of death for a cell,
as well as the biological implications and significance of programmed cell death. Recent developments in
the genetic control and interacting gene networks associated with apoptosis are presented. The book is written
for advanced undergraduate and postgraduate students, and is highly illustrated to aid understanding.
- Provides an accessible introduction to this important field, using non-specialist language to convey
the key concepts
- Covers both philosophical and practical aspects of cell death
- Uniquely discusses apoptosis in the context of stem cells
Contents
- 1. Dead or alive;
- 2. How to die;
- 3. What to wear and who clears up the rubbish;
- 4. To reproduce or
die;
- 5. The judge, jury, and executioner - the genes that control cell death;
- 6. Stem cells;
- 7. An in vivo
system to study apoptosis: the small intestine;
- 8. Cell death in diverse systems;
- 9. Measuring levels of cell
death.
To find similar publications, click on a keyword below:
Cambridge University Press
: cell biology
: textbook
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