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Anatomy of Gene Regulation - A Three-dimensional Structural Analysis
Panagiotis A. Tsonis
CUP
January 2003
Paperback 296 pp ISBN 0521804744
£35.00
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Hardback 296 pp ISBN 0521800307
£90.00
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No longer simple line drawings on a page, molecular structures can now be viewed in full-figured glory,
often in color and even with interactive possibilities. Anatomy of Gene Regulation is the first book to present the
parts and processes of gene regulation at the three-dimensional level. Vivid structures of nucleic acids and
their companion proteins are revealed in full-color, three-dimensional form. Beginning with a general introduction
to three-dimensional structures, the book looks at the organization of the genome, the structure of DNA, DNA
replication and transcription, splicing, protein synthesis, and ultimate protein death. Throughout, the text employs
a discussion of genetics and structural mechanics. The concise and unique synthesis of information will offer insight
into gene regulation, and into the development of methods to interfere with regulation at diseased states. This textbook
and its accompanying web site are appropriate for both undergraduate and graduate students in genetics, molecular
biology, structural biology, and biochemistry courses.
- The first textbook to present gene regulation at the three-dimensional level
- More than 250 color images
- Accompanying web site complements book
Contents
- Preface
- 1. A general introduction to 3-D structures;
- 2. The higher organization of the genome;
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3. Structure of DNA and telomeres;
- 4. DNA replication;
- 5. Transcription in prokaryotes;
- 6. Transcription
in eukaryotes;
- 7. Splicing;
- 8. Modifications of mRNA;
- 9. Compartmentalization of transcription;
- 10. Protein synthesis;
- 11. The birth and death of proteins;
- Index.
To find similar publications, click on a keyword below:
Cambridge University Press
: DNA
: genes
: molecular biology
: proteins
: textbook
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