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Handbook of Genome Research: Genomics, Proteomics, Metabolomics, Bioinformatics, Ethical and Legal Issues
Edited by Christoph W. Sensen
Wiley
June 2005
Hardcover, Two Volumes 646 pages ISBN 3527313486
£190.00
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In this unique presentation of a revolutionary field of science, the first section introduces the domains of application
for genomics and bioinformatics, such as sequencing and the comparative sequence analysis of model organisms,
investigating genetically influenced diseases, the development of new active substances, agri-food and environmental
genomics.
There then follows an overview of current topics central to DNA technologies, proteomics, metabolomics and
bioinformatics, including such hot topics as DNA chip fabrication, yeast two hybrid analysis, tools for gene
expression studies, metabolic networks and systems biology.
The whole is rounded off by four chapters on the ethical, legal and social aspects of this sensitive topic.
Contents
KEY ORGANISMS
- Genome Projects on Model Organisms
- Environmental Genomics: A Novel Tool for Study of Uncultivated Microorganisms
- Applications of Genomics in Plant Biology
II GENOMIC AND PROTEOMIC TECHNOLOGIES
- Human Genetic Diseases
- Genomic Mapping and Positional Cloning, with Emphasis on Plant Science
- DNA Sequencing Technology
- Proteomics and Mass Spectrometry for the Biological Researcher
- Proteome Analysis by Capillary Electrophoresis
- A DNA Microarray Fabrication Strategy for Research Laboratories
- Principles of Application of DNA Microarrays
- Yeast Two-hybrid Technologies
- Structural Genomics
III BIOINFORMATICS
- Bioinformatics Tools for DNA Technology
- Software Tools for Proteomics Technologies
- Applied Bioinformatics for Drug Discovery and Development
- Genome Data Representation Through Images: The MAGPIE/Bluejay System
- Bioinformatics Tools for Gene-expression Studies
- Protein Interaction Databases
- Bioinformatics Approaches for Metabolic Pathways
- Systems Biology
IV ETHICAL, LEGAL AND SOCIAL ISSUES
- Ethical Aspects of Genome Research and Banking
- Biobanks and the Challenges of Commercialization
- The (Im)perfect Human -
- His Own Creator? Bioethics and Genetics at the Beginning of Life
V OUTLOOK
- The Future of Large-Scale Life Science Research
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