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Bioinformatics: A Practical Guide to the Analysis of Genes and Proteins, 3rd Edition
Edited by Andreas D. Baxevanis and B. F. Francis Ouellette
Wiley
November 2004
Hardcover 540 pp ISBN 0471478784
£50.00
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This fully revised version of a world-renowned bestseller provides readers with a practical guide
covering the full scope of key concepts in bioinformatics, from databases to predictive and comparative
algorithms. Using relevant biological examples, the book provides background on and strategies for using
many of the most powerful and commonly used computational approaches for biological discovery.
This Third Edition reinforces key concepts that have stood the test of time while making the reader
aware of new and important developments in this fast-moving field. With a new full-color and enlarged
page design, Bioinformatics, Third Edition offers the most readable, up-to-date, and thorough introduction
to the field for biologists.
This new edition features:
- New chapters on genomic databases, predictive methods using RNA sequences, sequence
polymorphisms, protein structure prediction, intermolecular interactions, and proteomic approaches for
protein identification
- Detailed worked examples illustrating the strategic use of the concepts presented in each chapter,
along with a collection of expanded,more rigorous problem sets suitable for classroom use
- Special topic boxes and appendices highlighting experimental strategies and advanced concepts
- Annotated reference lists, comprehensive lists of relevant Web resources, and an extensive glossary
of commonly used terms in bioinformatics, genomics, and proteomics
Bioinformatics, Third Edition is essential reading for researchers, instructors, and students of all levels in
molecular biology and bioinformatics, as well as for investigators involved in genomics, clinical research,
proteomics, and computational biology.
Contents
Foreword (Lee Hood).
Preface.
Contributors.
PART ONE: BIOLOGICAL DATABASES.
1. Sequence Databases (Rolf Apweiler).
2. Mapping Databases (Peter S. White and Tara C. Matise).
3. Information Retrieval from Biological Databases (Andreas D. Baxevanis).
4. Genomic Databases (Tyra G. Wolfsberg).
PART TWO: ANALYSIS AT THE NUCLEOTIDE LEVEL.
5. Predictive Methods Using DNA Sequences (Enrique Blanco and Roderic Guigó).
6. Predictive Methods Using RNA Sequences (David Mathews and Michael Zuker).
7. Sequence Polymorphisms (James C. Mullikin and Stephen T. Sherry).
PART THREE: ANALYSIS AT THE PROTEIN LEVEL.
8. Predictive Methods Using Protein Sequences (Yanay Ofran and Burkhard Rost).
9. Protein Structure Prediction and Analysis (David Wishart).
10. Intermolecular Interactions and Biological Pathways (Gary D. Bader and Anton J. Enright).
PART FOUR: INFERRING RELATIONSHIPS.
11. Assessing Pairwise Sequence Similarity: BLAST and FASTA (Andreas D. Baxevanis).
12. Creation and Analysis of Protein Multiple Sequence Alignments (Geoffrey J. Barton).
13. Sequence Assembly and Finishing Methods (Nancy F. Hansen, Pamela Jacques Thomas and Gerard G. Bouffard).
14. Phylogenetic Analysis (Fiona S. L. Brinkman).
15. Computational Approaches in Comparative Genomics (Andreas D. Baxevanis).
16. Using DNA Microarrays to Assay Gene Expression (John Quackenbush).
17. Proteomics and Protein Identification (Mark R. Holmes, Kevin R. Ramkissoon and Morgan C. Giddings).
PART FIVE: DEVELOPING TOOLS.
18. Using Perl to Facilitate Biological Analysis (Lincoln D. Stein).
Appendices.
Glossary. Index.
To find similar publications, click on a keyword below:
Wiley
: analytical methods
: bioinformatics
: genes
: handbooks
: proteins
: sequencing
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