Prion Biology and Diseases, Second Edition

Hardback  1050 pp  ISBN 0879696931      £80.00

Contents

PRION BIOLOGY
Chapter 1: An Introduction to Prion Biology and Diseases S.B. Prusiner
Chapter 2: Development of the Prion Concept S.B. Prusiner
Chapter 3: Bioassays of Prions S.B. Prusiner, J. Safar, and S.J. DeArmond
Chapter 4: Transmission and Replication of Prions S.B. Prusiner, M.R. Scott, S.J. DeArmond, and G. Carlson
Chapter 5: Structural Studies of Prion Proteins C. Govaerts, H. Wille, S.B. Prusiner, and F.E. Cohen
Chapter 6: Doppel, a New PrP-like Mammalian Protein D. Westaway, L.E. Hood, and S.B. Prusiner

FUNGAL PRIONS
Chapter 7: Prions of Yeast and Filamentous Fungi: [URE3], [PSI+], [PIN+], and [Het's] R.B. Wickner, S.W. Liebman, and S.J. Saupe

TRANSGENETICS AND CELL BIOLOGY OF PRIONS
Chapter 8: Knockouts, Knockins, Transgenics, and Transplants in Prion Research E. Flechsig, J.C. Manson, R. Barron, A. Aguzzi, and C. Weissmann
Chapter 9: Transgenetic Investigations of the Species Barrier and Prion Strains M. Scott, D. Peretz, R.M. Ridley, H.F. Baker, S.J. DeArmond, and S.B. Prusiner
Chapter 10: Cell Biology of Prions D.A. Harris, P.J. Peters, A. Taraboulos, V. Lingappa, S.J. DeArmond, and S.B. Prusiner

PRION DISEASES IN ANIMALS
Chapter 11: Scrapie, Chronic Wasting Disease, and Transmissible Mink Encephalopathy S.B. Prusiner, E. Williams, J.-L. Laplanche, and M. Shinagawa
Chapter 12: Bovine Spongiform Encephalopathy and Related Diseases G.A.H. Wells and J.W. Wilesmith

HUMAN PRION DISEASES
Chapter 13: Infectious and Sporadic Prion Diseases R.G. Will, M.P. Alpers, D. Dormont, and L.B. Schonberger
Chapter 14: Inherited Prion Diseases Q. Kong, W.K. Surewicz, R.B. Petersen, W. Zou, S.G. Chen, P. Gambetti, P. Parchi, S. Capellari, L. Goldfarb, P. Montagna, E. Lugaresi, P. Piccardo, and B. Ghetti
Chapter 15: Neuropathology of Prion Diseases S.J. DeArmond, J.W. Ironside, E. Bouzamondo-Bernstein, D. Peretz, and J.R. Fraser

METHODOLOGY, BIOSAFETY, AND THERAPEUTICS
Chapter 16: Some Strategies and Methods for the Study of Prions S.B. Prusiner, G. Legname, S.J. DeArmond, F.E. Cohen, J. Safar, D. Riesner, and K. Kaneko
Chapter 17: Biosafety Issues in Prion Diseases H. Baron, J. Safar, D. Groth, S.J. DeArmond, and S.B. Prusiner
Chapter 18: Therapeutic Approaches to Prion Diseases S.B. Prusiner, B.C.H. May, and F.E. Cohen

Glossary
Appendix
Index