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A Genetic Switch, Third Edition, Phage Lambda Revisited

Mark Ptashne 
CSHL  2004  



Paperback  154 PP  ISBN 0879697164      £22.99
The first edition (1986) of this book describing the principles of gene regulation in phage lambda became a classic in both content and form, setting a standard of clarity and precise prose that has rarely been bettered. This edition is a reprint of the original text, together with a new chapter updating the story to 2004. Among the striking new developments are recent findings on long€range interactions between proteins bound to widely separated sites on the phage genome, and a detailed description of how gene activation works. Contents
  • Chapter 1. The Master Elements of Control
  • Chapter 2. Protein€DNA Interactions and Gene Control
  • Chapter 3. Control Circuits€Setting the Switch
  • Chapter 4. How Do We Know€The Key Experiments
  • Chapter 5. 2004: New Developments
  • Appendices
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Cold Spring Harbor : biochemistry : biology, general : cell biology : genetics : genomics : molecular biology

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