The Immunoassay Handbook - 3rd edition

Hardback  930 pp  ISBN 0080445268      £127.00

• This third edition contains updated and new information on advanced technology, including micro- and nanoscale immunoassays.
• Provides a unique mix of practical information coupled with a review of clinical applications, and practical examples
• Include contributions from world experts

Highly illustrated and clearly written, The Immunoassay Handbook provides an excellent guide to this fast-growing industry.

Revised and updated, this third edition offers a balanced review of practical information and clinical applications in the field of immunoassay technology.

Comprehensive and expertly written, The Immunoassay Handbook will be invaluable for a wide range of users from researchers developing immunoassay systems to developmental and marketing staff who need an excellent overview of how immunoassay principles, systems and applications work.

With 68 chapters covering a wide range of topics, and new chapters looking at: surface plasmon resonance in kinetic, concentration and binding site analyses, and the foundations of immunochemistry, this handbook is a must read for all laboratory researchers and academics who use immunoassay as a tool including: pathologists, clinical and veterinary chemists, biochemists, students and researchers in immunology, biochemistry and medicine.

Readership: Laboratory researchers and academics who use immunossay as a tool including pathologists, clinical and veterinary chemists, biochemists, students and researchers in immunology, biochemistry and medicine.

Contents

Part 1 Principles

• Introduction to immunoassay principles (C. Davies).
• Non-competitive immunoassays for small molecules - the anti-complex, selective antibody and apposition systems (C.H. Self et al.).
• Ambient analyte assay (R. Ekins).
• Free analyte immunoassay (N.D. Christofides).
• The foundations of immunochemistry NEW (R.F. Ritchie).
• Concepts (C. Davies).
• Immunoassay development in the in vitro diagnostic industry (D. Brandt, S. Figard).
• Antibodies (E. Liddell).
• Standardization and calibration (D. Wild).
• Separation Systems (D. Wild, W. Kusnezow).
• Signal Generation and Detection Systems (Excluding Homogeneous Assays) (L.J. Kricka, D. Wild).
• Homogeneous immunoassays (E.F. Ullman).
• Calibration curve-fitting (B. Nix, D. Wild).
• Conjugation methods (A.H. Dent).
• Immunological biosensors (J.K. Gimzewski et al.).
• Surface plasmon resonance in kinetic, concentration and binding site analyses (R. Karlsson et al.).
• Lab-on-a-chip, micro-and nanoscale immunoassay systems (L.J. Kricka, D. Wild).

• Introduction to product technology in clinical diagnostic testing (D. Wild).
• Market trends (D. Huckle, D. Wild).
• Choosing an automated immunoassay system (L.J. Sokoll, D.W. Chan).
• Automated system features (A. Truchaud et al.).
• Over-the-counter pregnancy test kits (M.J. Wheeler).
• Fluorescence microscopy: Microtrak (T. Houts).
• Automated batch analyzers: IMx (K. Ford).
• Automated bulk reagent random-access analyzers: UniCAP 100 (G. Evans, M. Rilvën).
• Automated panel analyzers: PRISM (D. Shah, J. Stewart).
• Unitized reagent random-access analyzers: IMMULITEReg and IMMULITE 1000 (A.L. Babson).
• Bulk reagent random-access analyzers: ACS:180Reg SE (E. Gramignano).
• Bulk reagent random-access analyzers: AxSYMReg (T. Donahoe).
• Bulk reagent random access analyzers: ElecsysReg Immunoassay Systems (T. Atkinson).
• Bulk reagent random-access analyzers: VitrosReg ECi (D. Wild).
• Bulk reagent random-access analyzers: IMMULITEReg2000 and IMMULITE 2500 (A.L. Babson).
• ulk reagent random-access analyzers: ADVIA CentaurReg (L. Taylor, E. Gramignano).
• Bulk reagent random-access analyzers: ARCHITECTReg i2000Reg and i2000SRReg analyzers (F.A. Quinn).
• CEDIATM, a homogeneous enzyme immunoassay system (W.A. Coty, R. Loor).
• Clinical Chemistry Analyzers: VITROSTMTM Immuno-Rate and MicroTipTM Assays (S.J. Danielson, D.A. Hilborn).
• Near-patient tests: the TriageReg system (K.F. Buechler).
• Near-patient tests: Stratusâ CS acute careTM diagnostic system (W.N. McLellan).
• Over-the-counter tests: Clearblue pregnancy testä, Clearblue ovulation testä and Clearviewä (K. May).
• Over-the-counter tests: Persona (K. May).

• Subject preparation, sample collection and handling (C. Wilde).
• Laboratory quality assurance (P. Blockx, M. Martin).
• Point-of-care testing (J.H. Nichols).
• Troubleshooting guide (D. Wild).

• Thyroid (R. John et al.).
• The Adrenal Cortex (S. Medbak).
• Bone metabolism (K.W. Colston, J.C. Stevenson).
• Infertility (M.J. Wheeler).
• In vitro fertilization and embryo transfer (IVF-ET) (A.C. Olivar).
• Hirsutism and virilization in the female (M.J. Wheeler).
• Pregnancy (T. Chard).
• Growth and growth hormone deficiency (M. Preece, J. Pringle).
• Diabetes mellitus (P. Clark).
• Hematology (D. Dawson et al.).
• Cardiac markers (A.H.B. Wu).
• Cancer markers (M.R. Suresh).
• Allergy (L. Yman).
• Autoimmune diseases (D.F. Keren M.D.).
• Sexually transmitted diseases (B.J. Dille et al.).
• Congenital diseases of microbiological origin (B.J. Dille et al.).
• Hepatitis (I.K. Mushahwar).
• Human retroviruses (G.J. Dawson, I.K. Mushahwar).
• Dengue virus infections (B.J. Dille, I.K. Mushahwar).
• Miscellaneous diseases of microbiological origin (B.J. Dille, I.K. Mushahwar).
• Therapeutic Drug Monitoring (TDM) (P.A. Routledge, A.D. Hutchings).
• Drugs of abuse (B. Widdop).
• Assays for drug-screening applications and research (J.K. Horton et al.).
• Immunoassay applications in veterinary diagnostics (E. Workman).