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Compact Handbook of Computational Biology
Edited by Andrzej K Konopka; M. James C. Crabbe
CRC Press
2004
Hardback 568 pp ISBN 0824709829
£54.00
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This book
- Describes the foundational concepts, techniques, and challenges unique to biomolecular sequence analysis, biopolymer
structure analysis and prediction, genomics, and molecular evolution
- Constitutes a reliable, integrated reference for specialists as well as an instructive manual for students and trainees in
computational biology and bioinformatics
- Presents authoritative descriptions of methods and practical examples of their correct use supported by over 975
works
cited
- Supplies one appendix devoted to computer programs for sequence analysis and another one that constitutes an
exhaustively annotated glossary of validated terms that pertain to computational, evolutionary and systems biology
The assimilation of computational methods into the life sciences has played an important role in advancing biological
research. From sequencing genomes to discovering motifs in large collections of functionally equivalent sequences
of nucleic acids and proteins, the value of powerful computational tools has become abundantly clear. The Compact
Handbook of Computational Biology describes the foundational concepts, techniques, and challenges of biomolecular
sequence analysis, biopolymer structure analysis and prediction, genomics, and molecular evolution.
Comprising contributions from renowned scientists, many of whom pioneered current methodologies, the Compact
Handbook of Computational Biology offers interdisciplinary and authoritative coverage of methods for analysis of
nucleic acid and protein sequences and structures, definition and detection of motifs in nucleic acid and protein
sequences, protein structure prediction, and discrete modeling of biopolymers. Specific computational topics include
computer-assisted research on protein folding, computer-assisted studies of DNA-protein interactions, computer-
assisted genomics, proteomics, and comparative genomics, and computer-assisted studies of genome evolution
at the molecular (DNA) level.
Offering a survey of specific algorithms that have proven successful in molecular biology, genomics, structural biology,
and bioinformatics, this invaluable handbook is an authoritative source covering terminology, software, and applications
of computational biology.
Contents
Foreword
Contributors
Introduction: Computational Biology in 14 Brief Paragraphs, A.K. Konopka and M.J.C. Crabbe
BIOMOLECULAR SEQUENCE ANALYSIS
Introduction to Pragmatic Analysis of Nucleic Acid Sequences, A.K. Konopka
Motifs in Sequences: Localization and Extraction, M. Crochemore and M-F. Sagot
Protein Sequence Analysis and Prediction of Secondary Structural Features, J. Heringa
BIOPOLYMER STRUCTURE CALCULATION AND PREDICTION
Discrete Models of Biopolymers, P. Schuster and P.F. Stadler
Protein Structure Folding and Prediction, W.R. Taylor
DNA-Protein Interactions: Target Prediction, A. Sarai and H. Kono
GENOME ANALYSIS AND EVOLUTION
Methods of Computational Genomics: An Overview, F. Lisacek
Computational Aspects of Comparative Genomics, W. Makalowski and I. Makalowska
Computational Methods for Studying the Evolution of the Mitochondrial Genome, C. Saccone and G. Pesole
Appendix 1: Computational Biology: Annotated Glossary of Terms, A.K. Konopka, P. Bucher, M.J.C. Crabbe,
M. Crochemore, J. Heringa, F. Lisacek, I. Makalowska, G. Pesole, C. Saccone, M-F. Sagot, A. Sarai, P. Stadler, and W.R. Taylor
Appendix 2: A Dictionary of Programs for Sequence Analysis, A.K. Konopka and J. Heringa
Index
To find similar publications, click on a keyword below:
CRC Press
: analytical methods
: biopolymers
: cell biology
: evolution
: genomics
: mathematics
: modelling, computer & mathematical
: sequencing
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