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Genomics and Proteomics in Nutrition

Edited by Carolyn D Berdanier; Naima Moustaid-Moussa 
CRC Press  2004  



Hardcover  528 pp  ISBN 9780824754303      £133.00
  • Investigates the latest proteomic studies for a clear understanding of the role of nutrients and drugs in nutrient and cellular metabolism
  • Presents selected examples showcasing the effect of phytochemicals on gene expression in different model systems
  • Identifies molecular markers associated with various disease states for improved diagnostic and treatment regimens
  • Familiarizes clinical investigators with the day-to-day problems encountered in the design, implementation, and evaluation of microarray analysis of clinical samples and provides the background necessary to develop solutions to these problems
With contributions from 66 world-renowned authorities on the subject, Genomics and Proteomics in Nutrition focuses on the effect of genetic expression on protein production, establishing links between gene expression and nutrition, the influence of micro- and macronutrients on cellular homeostasis, and the relationship between diet, genetic predisposition, and human disease. Applying innovations in microarray technology to clinical practice, this reference explores advances in our understanding of obesity, birth defects, and cancer, and shows how bioinformatics and functional genomic databases can transform molecular biology research using a yeast ELO2/ human HELO1 protein cloning example.

Contents


MOUSE MODELS OF HUMAN DISEASES AND GENE TRANSCRIPTION
Genetic Modifiers in Rodent Models of Obesity, Y. Wang, P.M. Nishina and J. Naggert
Quantitative TrAit Loci in obesity and TYPE II Diabetes in Rodents, J.H. Kim
The Human Sweet Tooth and its Relationship to Obesity, A.H. McDaniel and D.R. Reed
The Adipose Renin-Angiotensin System: Genetics, Regulation, and Physiologic Function, B.H. Voy, S. Kim, S. Urs, M. Derfus, Y.-R. Heo, R. Joshi, F. Massiera, M. Teboul, G. Aihaud, A. Quignard-Boulangé, and N. Moustaid-Moussa
Regulation of Fat Synthesis and Adipogenesis, K.-H. Kim, M.J. Griffin, J.A. Villena, and H.S. Sul
Transcriptional Regulation of Energy Metabolism in Liver, M.T. Nakamura,

GENOMICS: LARGE SCALE ANALYSIS OF GENE EXPRESSION BY MICROARRAY
Design and Analysis of Microarray Studies for Obesity Research, M.-Pierre St. Onge, G.P. Page, M. DeLuca, K. Zhang, K. Kim, S.B. Heymsfield, and D. Allsion
Solving Clinical Problems in Nutrition Research with Microarrays, S. Smith
Genomic Approaches to Understanding Vitamin D Action, J. Fleet
Gene Expression Profiling in Adipose Tissue, N. Moustaid-Moussa
Phytochemicals and Gene Expression, O. Mezei and N. Shay
Gene Expression Profiling of Immune Cells: Application for Understanding Aging of Immune Cells, S.N. Han and S. Meydani
Improving the Nutritional Value of Cereal Grains Using a Genomic Approach, L. Shi and T. Zhu

PROTEOMICS: LARGE SCALE ANALYSIS OF PROTEIN EXPRESSION AND REGULATION
Proteomics and Genomics in Health & Disease, J.A. Carroll and C.E. Mathews
2D-Gel Proteomics Studies on Leukocytes, I.C. Gerling and M.J. Pabst
Proteomics: Tools for Nutrition Research in the Post-Genomic Era, A. Grider
Proteomic Analysis of the Adipocyte Secretome, Ibarrola
Mass Spectrometry Strategies for Proteomic Studies, M. Belghazi and H. Rogniaux
Bioinformatics Tools, S.M Lin, K.F. Johnson, and S.W. Kullman
Statistical Principles for Analysis of Array Experiments, A.M. Saxton and E.B. Moser
Index

To find similar publications, click on a keyword below:
CRC Press : Phytochemicals : disease control : genomics : human health : mass spectrometry : microarrays : nutrition, human : proteomics

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