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Biophysical Aspects of Transmembrane Signaling
Edited by S Damjanovich
Springer
2005
Hardback 321 pp ISBN 3540250646
£130.00
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Transmembrane signaling is one of the most significant cell biological events in the life and
death of cells in general and lymphocytes in particular. Until recently biochemists and biophysicists were
not accustomed to thinking of these processes from the side of a high number of complex biochemical
events and an equally high number of physical changes at molecular and cellular levels at the same time.
Both types of researchers were convinced that their findings are the most decisive, having higher
importance than the findings of the other scientist population. Both casts were wrong. Life, even
at cellular level, has a number of interacting physical and biochemical mechanisms, which finally build up
the creation of an "excited" cell that will respond to particular signals from the outer or inner world.
This book handles both aspects of the signalling events, and in some cases tries to unify our concepts
and help understand the signals that govern the life and death of our cells. Not only the understanding,
but also the interference (e.g. medication) may depend on the full knowledge of both sides.
These above statements are supported by the application of highly diverse physical and biochemical
technologies demonstrated and explained by experts who are pioneers of their particular scientific field.
Contents
- 1 The Impact of Environmental Signals on the Growth and Survival of Human T Cells.
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2 Novel Single Cell Fluorescence Approaches in the Investigation of Signaling at the Cellular Level.
- 3 Non-Random Patterns of Membrane Proteins and Their Roles in Transmembrane Signaling.
- 4 Transmembrane Signals Mediated by IL-2 and IL-15 Control the Life and Death of Lymphocytes.
- 5 Single-Molecule Imaging of Diffusion, Recruitment, and Activation of Signaling Molecules in Living Cells.
- 6 Chemokine Signaling: The Functional Importance of Stabilizing Receptor Conformations.
- 7 Signaling and Reverse Signaling in the Tumor Necrosis Factor/TNF Receptor System.
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8 Regulation of Immunoreceptor Activities: The Paradigm of the Type I Fce Receptor.
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Histamine Receptors and Signaling.
- 10 Signal Transduction by Ion Channels in Lymphocytes
To find similar publications, click on a keyword below:
Springer
: T-cells
: biophysics
: immunology
: ion channels
: lymphocytes
: membranes
: signalling, plant
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