Introduction to Biocatalysis Using Enzymes and Microorganisms

Hardback  ISBN 0521430704      £45.00

Paperback  ISBN 0521436850      £20.00

This is an introductory text intended to give the non-specialist a comprehensive insight into the science of biotransformations. The book traces the history of biotransformations, clearly spells out the pros and cons of conducting enzyme-mediated versus whole-cell bioconversions and gives a variety of examples wherein the bio-reaction is a key element in a reaction sequence leading from cheap starting materials to valuable end-products (such as pharmaceuticals and agrochemicals, fragrances and flavours). Biotransformations involving the hydrolysis of esters, amides and nitriles, the synthesis of esters and amides, reduction and oxidation reactions and carbon-carbon bond-forming systems are discussed. The book finishes with a discussion of some industrially important large-scale bioconversions. The contents are as follows:

• An historical introduction to biocatalysis using enzymes and microorganisms
• The inter-relationship between enzymes and cells with particular reference to whole-cell biotransformations using bacteria and fungi
• Useful intermediates and end-products obtained from whole-cell/enzyme catalysed hydrolysis and esterification reactions
• Useful intermediates and end-products obtained from biocatalysed oxidation and reduction reactions
• Useful intermediates and end-products obtained from biocatalysed carbon-carbon, carbon-oxygen, carbon-nitrogen, and carbon-chalcogen bond-forming reactions
• The application of biocatalysis to the manufacture of fine chemicals
• Index.

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Cambridge University Press : agrobiologicals : beneficial microorganisms : biochemistry : biological conversion : bioproducts : biotechnology : cell biology : enzymology : microbiology : pharmaceuticals : speciality chemicals