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Microbial Protein Toxins
Edited by Manfred J Schmitt and Raffael Schaffrath
Springer
2005
Hardcover XIV + 237 pp ISBN 3540235620
£104.00
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Volume 11 in the series Topics in Current Genetics. Since the initial establishment of Robert Koch's
postulates in the nineteenth century, microbial protein toxins have been recognized as a major factor of bacterial
and fungal virulence. An increasing number of proteins produced and secreted by various bacteria, yeasts and
plants are extremely toxic and most of them developed remarkable strategies to enter, to penetrate and to finally kill
a eukaryotic target cell by modifying or blocking essential cellular components.
This book describes the strategies employed by protein toxins to give their pro and eukaryotic producers
a selective growth advantage over competitors. In providing an up-to-date overview on the mode of protein
toxin actions, it details biomedically and biologically relevant toxin model systems. As a result, it provides a broad
perspective on biochemical architecture and molecular interaction behind the lethal principles of pro and eukaryotic
toxins.
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